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Purified human C1-esterase inhibitor is safe in acute relapses of neuromyelitis optica

OBJECTIVE: To minimize complement-mediated damage in acute relapses of neuromyelitis optica (NMO) by adding treatment with a complement inhibitor, purified C1-esterase inhibitor, to the current standard of care (high-dose glucocorticoids). METHOD: We conducted an open-label phase 1b safety and proof...

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Detalles Bibliográficos
Autores principales: Levy, Michael, Mealy, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202676/
https://www.ncbi.nlm.nih.gov/pubmed/25340061
http://dx.doi.org/10.1212/NXI.0000000000000005