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Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton

OBJECTIVE: To examine the clinical features of pediatric CNS demyelination associated with positive myelin oligodendrocyte glycoprotein (MOG) antibodies and to examine the functional effects of MOG antibody on oligodendrocyte cytoskeleton. METHODS: We measured MOG antibody using a fluorescence-activ...

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Detalles Bibliográficos
Autores principales: Dale, Russell C., Tantsis, Esther M., Merheb, Vera, Kumaran, Raani-Yogeeta A., Sinmaz, Nese, Pathmanandavel, Karrnan, Ramanathan, Sudarshini, Booth, David R., Wienholt, Louise A., Prelog, Kristina, Clark, Damien R., Guillemin, Gilles J., Lim, Chai K., Mathey, Emily K., Brilot, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202678/
https://www.ncbi.nlm.nih.gov/pubmed/25340056
http://dx.doi.org/10.1212/NXI.0000000000000012