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Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton
OBJECTIVE: To examine the clinical features of pediatric CNS demyelination associated with positive myelin oligodendrocyte glycoprotein (MOG) antibodies and to examine the functional effects of MOG antibody on oligodendrocyte cytoskeleton. METHODS: We measured MOG antibody using a fluorescence-activ...
Autores principales: | Dale, Russell C., Tantsis, Esther M., Merheb, Vera, Kumaran, Raani-Yogeeta A., Sinmaz, Nese, Pathmanandavel, Karrnan, Ramanathan, Sudarshini, Booth, David R., Wienholt, Louise A., Prelog, Kristina, Clark, Damien R., Guillemin, Gilles J., Lim, Chai K., Mathey, Emily K., Brilot, Fabienne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202678/ https://www.ncbi.nlm.nih.gov/pubmed/25340056 http://dx.doi.org/10.1212/NXI.0000000000000012 |
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