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Thyroid Hormone-Regulated Cardiac microRNAs are Predicted to Suppress Pathological Hypertrophic Signaling

Cardiomyocyte size in the healthy heart is in part determined by the level of circulating thyroid hormone (TH). Higher levels of TH induce ventricular hypertrophy, primarily in response to an increase in hemodynamic load. Normal cardiac function is maintained in this form of hypertrophy, whereas pro...

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Detalles Bibliográficos
Autores principales: Janssen, Rob, Zuidwijk, Marian J., Kuster, Diederik W. D., Muller, Alice, Simonides, Warner S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202793/
https://www.ncbi.nlm.nih.gov/pubmed/25368602
http://dx.doi.org/10.3389/fendo.2014.00171