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Targeting of the β6 gene to suppress degradation of ECM via inactivation of the MAPK pathway in breast adenocarcinoma cells

Integrin ανβ6 has emerged as a potential novel target for anticancer and plays a major role in promoting malignant tumor progression. Recent studies indicate that integrin ανβ6 occurs in many cancers. However, whether and how ανβ6 is regulated by genetic and epigenetic mechanisms in breast cancer re...

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Detalles Bibliográficos
Autores principales: ZHANG, YUHUA, WEI, LIJING, YU, JIN, LI, GUANG, ZHANG, XIURU, WANG, ANLIU, HE, YANJIAO, LI, HONGLI, YIN, DELING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203328/
https://www.ncbi.nlm.nih.gov/pubmed/25176506
http://dx.doi.org/10.3892/or.2014.3419