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Salvaging hope: Is increasing NAD(+) a key to treating mitochondrial myopathy?

Mitochondrial diseases can arise from mutations either in mitochondrial DNA or in nuclear DNA encoding mitochondrially destined proteins. Currently, there is no cure for these diseases although treatments to ameliorate a subset of the symptoms are being developed. In this issue of EMBO Molecular Med...

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Detalles Bibliográficos
Autores principales: Lightowlers, Robert N, Chrzanowska-Lightowlers, Zofia MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203349/
https://www.ncbi.nlm.nih.gov/pubmed/24838280
http://dx.doi.org/10.15252/emmm.201404179