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Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2

Bacterial sepsis results in high mortality rates, and new therapeutics to control infection are urgently needed. Here, we investigate the therapeutic potential of fibrates in the treatment of bacterial sepsis and examine their effects on innate immunity. Fibrates significantly improved the survival...

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Detalles Bibliográficos
Autores principales: Tancevski, Ivan, Nairz, Manfred, Duwensee, Kristina, Auer, Kristina, Schroll, Andrea, Heim, Christiane, Feistritzer, Clemens, Hoefer, Julia, Gerner, Romana R, Moschen, Alexander R, Heller, Ingrid, Pallweber, Petra, Li, Xiaorong, Theurl, Markus, Demetz, Egon, Wolf, Anna M, Wolf, Dominik, Eller, Philipp, Ritsch, Andreas, Weiss, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203357/
https://www.ncbi.nlm.nih.gov/pubmed/24755316
http://dx.doi.org/10.1002/emmm.201303415