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On the origin of giant cells in Hodgkin lymphoma

Multinucleated giant tumor cells are frequently observed in tissue sections of lymphoma patients. In Hodgkin lymphoma (HL), these cells are pathognomonic for the disease and named Reed-Sternberg (RS) cells. Despite the well-described disease-promoting functions of RS cells, their development has rem...

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Detalles Bibliográficos
Autores principales: Rengstl, Benjamin, Rieger, Michael A., Newrzela, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203491/
https://www.ncbi.nlm.nih.gov/pubmed/25346790
http://dx.doi.org/10.4161/cib.28602