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Coronavirus NSP6 restricts autophagosome expansion

Autophagy is a cellular response to starvation that generates autophagosomes to carry long-lived proteins and cellular organelles to lysosomes for degradation. Activation of autophagy by viruses can provide an innate defense against infection, and for (+) strand RNA viruses autophagosomes can facili...

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Detalles Bibliográficos
Autores principales: Cottam, Eleanor M, Whelband, Matthew C, Wileman, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203519/
https://www.ncbi.nlm.nih.gov/pubmed/24991833
http://dx.doi.org/10.4161/auto.29309