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Androgen receptor, ccl2, and epithelial-mesenchymal transition: A dangerous affair in the tumor microenvironment

High levels of chemokine (C-C motif) ligand 2 (CCL2) promote the metastatic dissemination of prostate cancer by recruiting macrophages to neoplastic lesions. We have recently discovered that inhibiting the androgen receptor (AR) in prostate cancer cells or tumor-infiltrating macrophages results in t...

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Detalles Bibliográficos
Autores principales: Lin, Wen-Jye, Izumi, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203538/
https://www.ncbi.nlm.nih.gov/pubmed/25339999
http://dx.doi.org/10.4161/onci.27871