KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC

KIAA1524/CIP2A/cancerous inhibitor of protein phosphatase 2A is a cancer-promoting protein that stabilizes the MYC proto-oncogene protein by inhibiting its dephosphorylation. Our recent report demonstrates that KIAA1524/CIP2A supports cancer cell growth also at the level of the mechanistic target of...

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Detalles Bibliográficos
Autores principales: Puustinen, Pietri, Jäättelä, Marja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Autophagic Punctum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203564/
https://www.ncbi.nlm.nih.gov/pubmed/24905455
http://dx.doi.org/10.4161/auto.29076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203564/
https://www.ncbi.nlm.nih.gov/pubmed/24905455
http://dx.doi.org/10.4161/auto.29076

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