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Bone marrow-derived CD13(+) cells sustain tumor progression: A potential non-malignant target for anticancer therapy

Non-malignant cells found within neoplastic lesions express alanyl (membrane) aminopeptidase (ANPEP, best known as CD13), and CD13-null mice exhibit limited tumor growth and angiogenesis. We have recently demonstrated that a subset of bone marrow-derived CD11b(+)CD13(+) myeloid cells accumulate with...

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Detalles Bibliográficos
Autores principales: Dondossola, Eleonora, Corti, Angelo, Sidman, Richard L, Arap, Wadih, Pasqualini, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203577/
https://www.ncbi.nlm.nih.gov/pubmed/25339996
http://dx.doi.org/10.4161/onci.27716