Autophagy is increased in prostate cancer cells over-expressing acid ceramidase and enhances resistance to C(6)-ceramide

Acid ceramidase (AC) over-expression has been observed in prostate cancer cell lines and primary tumors, and contributes to resistance to chemotherapy and radiation. The consequence of AC over-expression is the ability to convert ceramide, which is often produced as a pro-apoptotic response to stres...

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Detalles Bibliográficos
Autores principales: Turner, Lorianne S., Cheng, Joseph C., Beckham, Thomas H., Norris, James S., Liu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203650/
https://www.ncbi.nlm.nih.gov/pubmed/21116286
http://dx.doi.org/10.1038/pcan.2010.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203650/
https://www.ncbi.nlm.nih.gov/pubmed/21116286
http://dx.doi.org/10.1038/pcan.2010.47

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