Oncomorphic TP53 Mutations in Gynecologic Cancers Lose the Normal Protein:Protein Interactions with the microRNA Microprocessing Complex

Mutations in the tumor suppressor TP53 occur in almost all advanced ovarian cancers and in many advanced serous endometrial cancers. Mutations in TP53 can alter the function of the p53 protein, and some mutations result in a mutated protein with oncogenic activity. Previously referred to as gain of...

Descripción completa

Detalles Bibliográficos
Autores principales: Brachova, Pavla, Mueting, Samuel R., Devor, Eric J., Leslie, Kimberly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203685/
https://www.ncbi.nlm.nih.gov/pubmed/25339994
http://dx.doi.org/10.4236/jct.2014.56058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203685/
https://www.ncbi.nlm.nih.gov/pubmed/25339994
http://dx.doi.org/10.4236/jct.2014.56058

Ejemplares similares