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The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease

Dysregulated endoplasmic reticulum (ER) calcium (Ca(2+)) signaling is reported to play an important role in Alzheimer disease (AD) pathogenesis. The role of ER Ca(2+) release channels, the ryanodine receptors (RyanRs), has been extensively studied in AD models and RyanR expression and activity are u...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Supnet, Charlene, Sun, Suya, Zhang, Hua, Good, Levi, Popugaeva, Elena, Bezprozvanny, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203752/
https://www.ncbi.nlm.nih.gov/pubmed/24476841
http://dx.doi.org/10.4161/chan.27471