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The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease
Dysregulated endoplasmic reticulum (ER) calcium (Ca(2+)) signaling is reported to play an important role in Alzheimer disease (AD) pathogenesis. The role of ER Ca(2+) release channels, the ryanodine receptors (RyanRs), has been extensively studied in AD models and RyanR expression and activity are u...
Autores principales: | Liu, Jie, Supnet, Charlene, Sun, Suya, Zhang, Hua, Good, Levi, Popugaeva, Elena, Bezprozvanny, Ilya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203752/ https://www.ncbi.nlm.nih.gov/pubmed/24476841 http://dx.doi.org/10.4161/chan.27471 |
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