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Bisphenol A activates BK channels through effects on α and β1 subunits

We demonstrated previously that BK (K(Ca)1.1) channel activity (NP(o)) increases in response to bisphenol A (BPA). Moreover, BK channels containing regulatory β1 subunits were more sensitive to the stimulatory effect of BPA. How BPA increases BK channel NP(o) remains mostly unknown. Estradiol activa...

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Detalles Bibliográficos
Autores principales: Rottgen, Trey S, Fancher, Ibra S, Asano, Shinichi, Widlanski, Theodore S, Dick, Gregory M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203754/
https://www.ncbi.nlm.nih.gov/pubmed/24476761
http://dx.doi.org/10.4161/chan.27709