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Investigating the size and dynamics of voltage-gated sodium channel fenestrations: A molecular dynamics study

Eukaryotic voltage-gated sodium channels (VGSCs) are essential for the initiation and propagation of action potentials in electrically excitable cells, and are important pharmaceutical targets for the treatment of neurological disorders such as epilepsy, cardiac arrhythmias, and chronic pain. Eviden...

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Detalles Bibliográficos
Autores principales: Kaczmarski, Joe A, Corry, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203756/
https://www.ncbi.nlm.nih.gov/pubmed/24632677
http://dx.doi.org/10.4161/chan.28136