Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

The sphingosine-1-phosphate (S1P) transporter Spns2 regulates myocardial precursor migration in zebrafish and lymphocyte trafficking in mice. However, its function in cancer has not been investigated. We show here that ectopic Spns2 expression induced apoptosis and its knockdown enhanced cell migrat...

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Detalles Bibliográficos
Autores principales: Bradley, Eric, Dasgupta, Somsankar, Jiang, Xue, Zhao, Xiaying, Zhu, Gu, He, Qian, Dinkins, Michael, Bieberich, Erhard, Wang, Guanghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203763/
https://www.ncbi.nlm.nih.gov/pubmed/25330231
http://dx.doi.org/10.1371/journal.pone.0110119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203763/
https://www.ncbi.nlm.nih.gov/pubmed/25330231
http://dx.doi.org/10.1371/journal.pone.0110119

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