The “Genomic Storm” Induced by Bacterial Endotoxin Is Calmed by a Nuclear Transport Modifier That Attenuates Localized and Systemic Inflammation

Lipopolysaccharide (LPS) is a potent microbial virulence factor that can trigger production of proinflammatory mediators involved in the pathogenesis of localized and systemic inflammation. Importantly, the role of nuclear transport of stress responsive transcription factors in this LPS-generated “g...

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Detalles Bibliográficos
Autores principales: DiGiandomenico, Antonio, Veach, Ruth Ann, Zienkiewicz, Jozef, Moore, Daniel J., Wylezinski, Lukasz S., Hutchens, Martha A., Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203769/
https://www.ncbi.nlm.nih.gov/pubmed/25329889
http://dx.doi.org/10.1371/journal.pone.0110183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203769/
https://www.ncbi.nlm.nih.gov/pubmed/25329889
http://dx.doi.org/10.1371/journal.pone.0110183

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