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Distribution of CYP2D6 Alleles and Phenotypes in the Brazilian Population

The CYP2D6 enzyme is one of the most important members of the cytochrome P450 superfamily. This enzyme metabolizes approximately 25% of currently prescribed medications. The CYP2D6 gene presents a high allele heterogeneity that determines great inter-individual variation. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Friedrich, Deise C., Genro, Júlia P., Sortica, Vinicius A., Suarez-Kurtz, Guilherme, de Moraes, Maria Elizabete, Pena, Sergio D. J., dos Santos, Ândrea K. Ribeiro, Romano-Silva, Marco A., Hutz, Mara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203818/
https://www.ncbi.nlm.nih.gov/pubmed/25329392
http://dx.doi.org/10.1371/journal.pone.0110691