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Distribution of CYP2D6 Alleles and Phenotypes in the Brazilian Population
The CYP2D6 enzyme is one of the most important members of the cytochrome P450 superfamily. This enzyme metabolizes approximately 25% of currently prescribed medications. The CYP2D6 gene presents a high allele heterogeneity that determines great inter-individual variation. The aim of this study was t...
Autores principales: | Friedrich, Deise C., Genro, Júlia P., Sortica, Vinicius A., Suarez-Kurtz, Guilherme, de Moraes, Maria Elizabete, Pena, Sergio D. J., dos Santos, Ândrea K. Ribeiro, Romano-Silva, Marco A., Hutz, Mara H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203818/ https://www.ncbi.nlm.nih.gov/pubmed/25329392 http://dx.doi.org/10.1371/journal.pone.0110691 |
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