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Traumatic brain injury causes selective, CD74-dependent peripheral lymphocyte activation that exacerbates neurodegeneration

INTRODUCTION: Traumatic brain injury (TBI), a significant cause of death and disability, causes, as in any injury, an acute, innate immune response. A key component in the transition between innate and adaptive immunity is the processing and presentation of antigen by professional antigen presenting...

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Detalles Bibliográficos
Autores principales: Tobin, Richard P, Mukherjee, Sanjib, Kain, Jessica M, Rogers, Susannah K, Henderson, Stephanie K, Motal, Heather L, Rogers, M Karen Newell, Shapiro, Lee A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203873/
https://www.ncbi.nlm.nih.gov/pubmed/25329434
http://dx.doi.org/10.1186/s40478-014-0143-5