A general framework for analyzing tumor subclonality using SNP array and DNA sequencing data

Intra-tumor heterogeneity reflects cancer genome evolution and provides key information for diagnosis and treatment. When bulk tumor tissues are profiled for somatic copy number alterations (sCNA) and point mutations, it may be difficult to estimate their cellular fractions when a mutation falls wit...

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Detalles Bibliográficos
Autores principales: Li, Bo, Li, Jun Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203890/
https://www.ncbi.nlm.nih.gov/pubmed/25253082
http://dx.doi.org/10.1186/s13059-014-0473-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203890/
https://www.ncbi.nlm.nih.gov/pubmed/25253082
http://dx.doi.org/10.1186/s13059-014-0473-4

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