Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

The mutational repertoire of cancers creates the neoepitopes that make cancers immunogenic. Here, we introduce two novel tools that identify, with relatively high accuracy, the small proportion of neoepitopes (among the hundreds of potential neoepitopes) that protect the host through an antitumor T...

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Detalles Bibliográficos
Autores principales: Duan, Fei, Duitama, Jorge, Al Seesi, Sahar, Ayres, Cory M., Corcelli, Steven A., Pawashe, Arpita P., Blanchard, Tatiana, McMahon, David, Sidney, John, Sette, Alessandro, Baker, Brian M., Mandoiu, Ion I., Srivastava, Pramod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203949/
https://www.ncbi.nlm.nih.gov/pubmed/25245761
http://dx.doi.org/10.1084/jem.20141308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203949/
https://www.ncbi.nlm.nih.gov/pubmed/25245761
http://dx.doi.org/10.1084/jem.20141308

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