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Tissue specific CD4(+) T cell priming determines the requirement for interleukin-23 in experimental arthritis

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease with striking heterogeneity in (i) clinical presentation, (ii) autoantibody profiles and (iii) responses to treatment suggesting that distinct molecular mechanisms may underlie the disease process. Proteoglycan-induced arthrit...

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Detalles Bibliográficos
Autores principales: Olalekan, Susan A, Cao, Yanxia, Finnegan, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203961/
https://www.ncbi.nlm.nih.gov/pubmed/25253467
http://dx.doi.org/10.1186/s13075-014-0440-1