Cargando…

Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid–lysophosphatidic acid receptor 1 cascade

INTRODUCTION: Lysophosphatidic acid (LPA) is a bioactive lipid that binds to G protein–coupled receptors (LPA(1–6)). Recently, we reported that abrogation of LPA receptor 1 (LPA(1)) ameliorated murine collagen-induced arthritis, probably via inhibition of inflammatory cell migration, Th17 differenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyabe, Yoshishige, Miyabe, Chie, Iwai, Yoshiko, Yokoyama, Waka, Sekine, Chiyoko, Sugimoto, Kazutaka, Harigai, Masayoshi, Miyasaka, Masayuki, Miyasaka, Nobuyuki, Nanki, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203966/
https://www.ncbi.nlm.nih.gov/pubmed/25273676
http://dx.doi.org/10.1186/s13075-014-0461-9