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LOS oligosaccharide modification enhances dendritic cell responses to meningococcal native outer membrane vesicles expressing a non-toxic lipid A

Outer membrane vesicles (OMV) are released by many bacteria, and contain immunogenic antigens in addition to harmful inflammatory factors, like lipopolysaccharides. Chemically detoxified OMV have been used in vaccines against Neisseria meningitidis (Nm); however, little is known about their interact...

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Detalles Bibliográficos
Autores principales: Jones, Hannah E, Copland, Alastair, Hamstra, Hendrik Jan, Cohen, Jonathan, Brown, Jeremy, Klein, Nigel, van der Ley, Peter, Dixon, Garth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204155/
https://www.ncbi.nlm.nih.gov/pubmed/24152255
http://dx.doi.org/10.1111/cmi.12231