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Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons

The instant blood-mediated inflammatory reaction (IBMIR) is a major obstacle to the engraftment of intraportal pig islet xenografts in primates. Higher expression of the galactose-α1,3-galactose (αGal) xenoantigen on neonatal islet cell clusters (NICC) than on adult pig islets may provoke a stronger...

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Detalles Bibliográficos
Autores principales: Hawthorne, W J, Salvaris, E J, Phillips, P, Hawkes, J, Liuwantara, D, Burns, H, Barlow, H, Stewart, A B, Peirce, S B, Hu, M, Lew, A M, Robson, S C, Nottle, M B, D'Apice, A J F, O'Connell, P J, Cowan, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204157/
https://www.ncbi.nlm.nih.gov/pubmed/24842781
http://dx.doi.org/10.1111/ajt.12722