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Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons
The instant blood-mediated inflammatory reaction (IBMIR) is a major obstacle to the engraftment of intraportal pig islet xenografts in primates. Higher expression of the galactose-α1,3-galactose (αGal) xenoantigen on neonatal islet cell clusters (NICC) than on adult pig islets may provoke a stronger...
Autores principales: | Hawthorne, W J, Salvaris, E J, Phillips, P, Hawkes, J, Liuwantara, D, Burns, H, Barlow, H, Stewart, A B, Peirce, S B, Hu, M, Lew, A M, Robson, S C, Nottle, M B, D'Apice, A J F, O'Connell, P J, Cowan, P J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204157/ https://www.ncbi.nlm.nih.gov/pubmed/24842781 http://dx.doi.org/10.1111/ajt.12722 |
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