Targeting Nrf2 Signaling to Combat Chemoresistance

Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that upregulates expression of a battery of genes to combat oxidative and electrophilic stress. Modification of Kelch-like ECH-associated protein 1 (Keap1) by reactive oxygen species stabilizes Nrf2 by escaping from degradation. Nrf...

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Detalles Bibliográficos
Autores principales: No, Jae Hong, Kim, Yong-Beom, Song, Yong Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204167/
https://www.ncbi.nlm.nih.gov/pubmed/25337579
http://dx.doi.org/10.15430/JCP.2014.19.2.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204167/
https://www.ncbi.nlm.nih.gov/pubmed/25337579
http://dx.doi.org/10.15430/JCP.2014.19.2.111

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