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Accumulation and therapeutic modulation of 6-sulfo LacNAc(+) dendritic cells in multiple sclerosis

OBJECTIVE: To examine the potential role of 6-sulfo LacNAc(+) (slan) dendritic cells (DCs) displaying pronounced proinflammatory properties in the pathogenesis of multiple sclerosis (MS). METHODS: We determined the presence of slanDCs in demyelinated brain lesions and CSF samples of patients with MS...

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Detalles Bibliográficos
Autores principales: Thomas, Katja, Dietze, Kristin, Wehner, Rebekka, Metz, Imke, Tumani, Hayrettin, Schultheiß, Thorsten, Günther, Claudia, Schäkel, Knut, Reichmann, Heinz, Brück, Wolfgang, Schmitz, Marc, Ziemssen, Tjalf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204231/
https://www.ncbi.nlm.nih.gov/pubmed/25340085
http://dx.doi.org/10.1212/NXI.0000000000000033