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Homotypic clusters of transcription factor binding sites: A model system for understanding the physical mechanics of gene expression

The organization of binding sites in cis-regulatory elements (CREs) can influence gene expression through a combination of physical mechanisms, ranging from direct interactions between TF molecules to DNA looping and transient chromatin interactions. The study of simple and common building blocks in...

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Detalles Bibliográficos
Autores principales: Ezer, Daphne, Zabet, Nicolae Radu, Adryan, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204428/
https://www.ncbi.nlm.nih.gov/pubmed/25349675
http://dx.doi.org/10.1016/j.csbj.2014.07.005