p53 Family and Cellular Stress Responses in Cancer

p53 is an important tumor suppressor gene, which is stimulated by cellular stress like ionizing radiation, hypoxia, carcinogens, and oxidative stress. Upon activation, p53 leads to cell-cycle arrest and promotes DNA repair or induces apoptosis via several pathways. p63 and p73 are structural homolog...

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Detalles Bibliográficos
Autores principales: Pflaum, Johanna, Schlosser, Sophie, Müller, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204435/
https://www.ncbi.nlm.nih.gov/pubmed/25374842
http://dx.doi.org/10.3389/fonc.2014.00285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204435/
https://www.ncbi.nlm.nih.gov/pubmed/25374842
http://dx.doi.org/10.3389/fonc.2014.00285

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