A computer-based quantitative systems pharmacology model of negative symptoms in schizophrenia: exploring glycine modulation of excitation-inhibition balance

Although many antipsychotics can reasonably control positive symptoms in schizophrenia, patients' return to society is often hindered by negative symptoms and cognitive deficits. As an alternative to animal rodent models that are often not very predictive for the clinical situation, we develope...

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Detalles Bibliográficos
Autores principales: Spiros, Athan, Roberts, Patrick, Geerts, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204440/
https://www.ncbi.nlm.nih.gov/pubmed/25374541
http://dx.doi.org/10.3389/fphar.2014.00229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204440/
https://www.ncbi.nlm.nih.gov/pubmed/25374541
http://dx.doi.org/10.3389/fphar.2014.00229

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