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Valproic acid potentiates curcumin-mediated neuroprotection in lipopolysaccharide induced rats

The etiology of neuroinflammation is complex and comprises multifactorial, involving both genetic and environmental factors during which diverse genetic and epigenetic modulations are implicated. Curcumin (Cur) and valproic acid (VPA), histone deacetylase 1 inhibitor, have neuroprotective effects. T...

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Detalles Bibliográficos
Autores principales: Zaky, Amira, Mahmoud, Mariam, Awad, Doaa, El Sabaa, Bassma M., Kandeel, Kamal M., Bassiouny, Ahmad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204527/
https://www.ncbi.nlm.nih.gov/pubmed/25374508
http://dx.doi.org/10.3389/fncel.2014.00337