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Methylated DNA is over-represented in whole-genome bisulfite sequencing data

The development of whole-genome bisulfite sequencing (WGBS) has resulted in a number of exciting discoveries about the role of DNA methylation leading to a plethora of novel testable hypotheses. Methods for constructing sodium bisulfite-converted and amplified libraries have recently advanced to the...

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Detalles Bibliográficos
Autores principales: Ji, Lexiang, Sasaki, Takahiko, Sun, Xiaoxiao, Ma, Ping, Lewis, Zachary A., Schmitz, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204604/
https://www.ncbi.nlm.nih.gov/pubmed/25374580
http://dx.doi.org/10.3389/fgene.2014.00341