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The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes

In the brain, astrocytes represent the cellular population that expresses the highest amount of connexins (Cxs). This family of membrane proteins is the molecular constituent of gap junction channels and hemichannels that provide pathways for direct cytoplasm-to-cytoplasm and inside-out exchange, re...

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Detalles Bibliográficos
Autores principales: Abudara, Verónica, Bechberger, John, Freitas-Andrade, Moises, De Bock, Marijke, Wang, Nan, Bultynck, Geert, Naus, Christian C., Leybaert, Luc, Giaume, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204617/
https://www.ncbi.nlm.nih.gov/pubmed/25374505
http://dx.doi.org/10.3389/fncel.2014.00306