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TP73 allelic expression in human brain and allele frequencies in Alzheimer's disease

BACKGROUND: The p73 protein, a paralogue of the p53 tumor suppressor, is essential for normal development and survival of neurons. TP73 is therefore of interest as a candidate gene for Alzheimer's disease (AD) susceptibility. TP73 mRNA is transcribed from three promoters, termed P1 – P3, and th...

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Detalles Bibliográficos
Autores principales: Li, Quanyi, Athan, Eleni S, Wei, Michelle, Yuan, Eric, Rice, Samuel L, Vonsattel, Jean-Paul, Mayeux, Richard P, Tycko, Benjamin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420466/
https://www.ncbi.nlm.nih.gov/pubmed/15175114
http://dx.doi.org/10.1186/1471-2350-5-14