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Parthenolide Sensitizes Human Colorectal Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand through Mitochondrial and Caspase Dependent Pathway

BACKGROUND/AIMS: Combination therapy utilizing tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in conjunction with other anticancer agents, is a promising strategy to overcome TRAIL resistance in malignant cells. Recently, parthenolide (PT) has proved to be a promising anticanc...

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Detalles Bibliográficos
Autores principales: Trang, Kieu Thi Thu, Kim, Se-Lim, Park, Sang-Bae, Seo, Seung-Young, Choi, Chung-Hwan, Park, Jin-Kyoung, Moon, Jin-Chang, Lee, Soo-Teik, Kim, Sang-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204686/
https://www.ncbi.nlm.nih.gov/pubmed/25349561
http://dx.doi.org/10.5217/ir.2014.12.1.34