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Lifespan Based Pharmacokinetic-Pharmacodynamic Model of Tumor Growth Inhibition by Anticancer Therapeutics

Accurate prediction of tumor growth is critical in modeling the effects of anti-tumor agents. Popular models of tumor growth inhibition (TGI) generally offer empirical description of tumor growth. We propose a lifespan-based tumor growth inhibition (LS TGI) model that describes tumor growth in a xen...

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Detalles Bibliográficos
Autores principales: Mo, Gary, Gibbons, Frank, Schroeder, Patricia, Krzyzanski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204849/
https://www.ncbi.nlm.nih.gov/pubmed/25333487
http://dx.doi.org/10.1371/journal.pone.0109747