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The Impact of HIF1α on the Per2 Circadian Rhythm in Renal Cancer Cell Lines

In mammals, the circadian rhythm central generator consists of interactions among clock genes, including Per1/2/3, Cry1/2, Bmal1, and Clock. Circadian rhythm disruption may lead to increased risk of cancer in humans, and deregulation of clock genes has been implicated in many types of cancers. Among...

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Detalles Bibliográficos
Autores principales: Okabe, Takashi, Kumagai, Megumi, Nakajima, Yoshihiro, Shirotake, Suguru, Kodaira, Kiichiro, Oyama, Masafumi, Ueno, Munehisa, Ikeda, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204850/
https://www.ncbi.nlm.nih.gov/pubmed/25333958
http://dx.doi.org/10.1371/journal.pone.0109693