Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

BACKGROUND: The expression of the rodent phosphoinositide-specific phospholipase C δ-4 (PLCδ4) has been found to be elevated upon mitogenic stimulation and expression analysis have linked the upregulation of PLCδ4 expression with rapid proliferation in certain rat transformed cell lines. The human h...

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Detalles Bibliográficos
Autores principales: Leung, David W, Tompkins, Chris, Brewer, Jim, Ball, Alexey, Coon, Mike, Morris, Valerie, Waggoner, David, Singer, Jack W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420486/
https://www.ncbi.nlm.nih.gov/pubmed/15140260
http://dx.doi.org/10.1186/1476-4598-3-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420486/
https://www.ncbi.nlm.nih.gov/pubmed/15140260
http://dx.doi.org/10.1186/1476-4598-3-15

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