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Human Translation Initiation Factor eIF4G1 Possesses a Low-Affinity ATP Binding Site Facing the ATP-Binding Cleft of eIF4A in the eIF4G/eIF4A Complex

[Image: see text] Eukaryotic translation initiation factor 4G (eIF4G) plays a crucial role in translation initiation, serving as a scaffolding protein binding several other initiation factors, other proteins, and RNA. Binding of eIF4G to the ATP-dependent RNA helicase eukaryotic translation initiati...

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Detalles Bibliográficos
Autores principales: Akabayov, Sabine R., Akabayov, Barak, Wagner, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204880/
https://www.ncbi.nlm.nih.gov/pubmed/25255371
http://dx.doi.org/10.1021/bi500600m