Measurement and Characterization of Superoxide Generation from Xanthine Dehydrogenase: A Redox-Regulated Pathway of Radical Generation in Ischemic Tissues

[Image: see text] The enzyme xanthine oxidoreductase (XOR) is an important source of oxygen free radicals and related postischemic injury. Xanthine dehydrogenase (XDH), the major form of XOR in tissues, can be converted to xanthine oxidase (XO) by oxidation of sulfhydryl residues or by proteolysis....

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Detalles Bibliográficos
Autores principales: Lee, Masaichi-Chang-il, Velayutham, Murugesan, Komatsu, Tomoko, Hille, Russ, Zweier, Jay L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204892/
https://www.ncbi.nlm.nih.gov/pubmed/25243829
http://dx.doi.org/10.1021/bi500582r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204892/
https://www.ncbi.nlm.nih.gov/pubmed/25243829
http://dx.doi.org/10.1021/bi500582r

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