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Long term physiologic modification using rAAV in utero gene-therapy

BACKGROUND: Transfer of genes in utero via the amniotic fluid was shown previously with recombinant adeno-associated viruses (rAAV) to be highly efficient. Expression for over one year was demonstrated using reporter genes. In addition, it was shown previously that transgenes delivered by this metho...

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Detalles Bibliográficos
Autores principales: Garrett, Deiadra J, Cohen, J Craig, Larson, Janet E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420496/
https://www.ncbi.nlm.nih.gov/pubmed/15151697
http://dx.doi.org/10.1186/1479-0556-2-4