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Long term physiologic modification using rAAV in utero gene-therapy
BACKGROUND: Transfer of genes in utero via the amniotic fluid was shown previously with recombinant adeno-associated viruses (rAAV) to be highly efficient. Expression for over one year was demonstrated using reporter genes. In addition, it was shown previously that transgenes delivered by this metho...
Autores principales: | Garrett, Deiadra J, Cohen, J Craig, Larson, Janet E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420496/ https://www.ncbi.nlm.nih.gov/pubmed/15151697 http://dx.doi.org/10.1186/1479-0556-2-4 |
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