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Lack of XBP-1 Impedes Murine Cytomegalovirus Gene Expression

The unfolded protein response (UPR) is an endoplasmic reticulum (ER)-to-nucleus signaling cascade induced in response to ER stress. The UPR aims at restoring homeostasis, but can also induce apoptosis if stress persists. Infection by human and murine cytomegaloviruses (CMVs) provokes ER stress and i...

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Detalles Bibliográficos
Autores principales: Drori, Adi, Messerle, Martin, Brune, Wolfram, Tirosh, Boaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205010/
https://www.ncbi.nlm.nih.gov/pubmed/25333725
http://dx.doi.org/10.1371/journal.pone.0110942