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Minority Drug-Resistant HIV-1 Variants in Treatment Naïve East-African and Caucasian Patients Detected by Allele-Specific Real-Time PCR

OBJECTIVE: To assess the presence of two major non-nucleoside reverse transcriptase inhibitors (NNRTI) drug resistance mutations (DRMs), Y181C and K103N, in minor viral quasispecies of treatment naïve HIV-1 infected East-African and Swedish patients by allele-specific polymerase chain reaction (AS-P...

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Detalles Bibliográficos
Autores principales: Ekici, Halime, Amogne, Wondwossen, Aderaye, Getachew, Lindquist, Lars, Sönnerborg, Anders, Abdurahman, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205091/
https://www.ncbi.nlm.nih.gov/pubmed/25333961
http://dx.doi.org/10.1371/journal.pone.0111042