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A Novel Controllable Hydrogen Sulfide-Releasing Molecule Protects Human Skin Keratinocytes Against Methylglyoxal-Induced Injury and Dysfunction

BACKGROUND/AIM: Delayed wound healing is a common skin complication of diabetes, which is associated with keratinocyte injury and dysfunction. Levels of methylglyoxal (MGO), an α-dicarbonyl compound, are elevated in diabetic skin tissue and plasma, while levels of hydrogen sulfide (H(2)S), a critica...

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Detalles Bibliográficos
Autores principales: Yang, Chun-tao, Zhao, Yu, Xian, Ming, Li, Jian-hua, Dong, Qi, Bai, Hong-bo, Xu, Ji-de, Zhang, Mei-fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205174/
https://www.ncbi.nlm.nih.gov/pubmed/25277151
http://dx.doi.org/10.1159/000366339